terminal complement complex การใช้

• Eculizumab inhibits the cleavage of C5a ( a potent anaphylatoxin with prothrombotic and proinflammatory properties ) and C5b by the C5 convertase, which prevents the generation of the terminal complement complex C5b-9 ( which also has prothrombotic and proinflammatory effects ).
• The "'membrane attack complex "'( "'MAC "') or "'terminal complement complex "'( "'TCC "') is a structure typically formed on the surface of pathogenic bacterial classical pathway, or lectin pathway of the complement system, and it is one of the effector proteins of the immune system.